Transient Ischaemic Attack

A recent clinical practice article in the NEJM(1) on Transient Ischaemic Attack (TIA) gave a nice summary of this topic. Current guidelines that are good reference sources on stroke and TIA management include: American Heart Association and the American Stroke Association (AHA–ASA),(2) NICE,(3) and the European Stroke Organization(4) Definition of TIA The new definition of…

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A new DAWN for stroke treatment

Last week we looked at a case study involving a patient who awoke with stroke symptoms. In these cases there has been little to offer patients. Thrombolysis has no application here, given its 3-4 hour window. Endovascular mechanical thrombectomy has been hailed as the new treatment. Until January of 2018, trials in this area demonstrated…

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Magnesium Sulfate: Neuroprotective in Stroke? Study says no.

We have had a longstanding and controversial discussion about thrombolysis and definitive management of stroke, however, there is a unified front in trying to find a neuroprotective agent, that somehow shields the cells from damage. Over 70 different such agents have been tried in the past, with no success. One of the main criticisms relating…

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