Does Fluid Restriction in Septic Shock result in Better Outcomes?

Literature Review: Restriction of Intravenous Fluids in ICU Patients with Septic Shock. NEJM 386;26. June 30,2022 pp2459-2470. In patients with septic shock, higher volumes of intravenous fluids have been associated with worst outcomes. These included kidney injury, respiratory failure and an increased risk of death. Most of these conclusions came from randomised trials and observational…

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